Behavioral and Physical Activity Interventions for HAND.
Autor: Montoya, Jessica L.; Henry, Brook; Moore, David J.
Publication year: 2021
Current topics in behavioral neurosciences
issn:1866-3370 1866-3389
doi: 10.1007/7854_2018_79
Abstract:
Approximately 30-50% of persons living with HIV manifest some degree of neurocognitive impairment. Even mild-to-moderate forms of HIV-associated neurocognitive disorders (HAND) can result in difficulties with everyday functioning, such as suboptimal medication adherence and impaired driving. Despite the pervasive presence and consequences of HAND, there is a significant unmet need to develop effective behavioral strategies to reduce the incidence and consequences of HAND. Although there is an absence of evidence-based behavioral interventions specific to HAND, the literature reviewed in this chapter suggest the following modifiable lifestyle factors as intervention targets: physical activity, diet, sleep, and antiretroviral medication adherence. Adoption and maintenance of these healthy lifestyle factors may reduce inflammation and oxidative stress, which, in turn, may reduce the incidence and/or severity of HAND.
Language: eng
Rights: © 2019. Springer Nature Switzerland AG.
Pmid: 30694458
Tags: Humans; Cognition; Exercise; Sleep; Diet; Physical activity; *HIV Infections/complications/drug therapy; Nutrition; *Neurocognitive Disorders; Antiretroviral therapy adherence
Link: https://pubmed.ncbi.nlm.nih.gov/30694458/
