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A Case of Aplastic Anemia Associated With Long-Term Metronidazole Use.

PubMed
May 4, 2025
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Autor: Sam, Andrew M.; Saunders, Ila M.; Taplitz, Randy; Koura, Divya

Publication year: 2020

Journal of pharmacy practice

issn:1531-1937 0897-1900

doi: 10.1177/0897190019825584

Abstract:

Metronidazole is a nitroimidazole antibacterial agent that is highly effective for the treatment of protozoal and anaerobic infections. Metronidazole is known to cause hematologic adverse effects, including a reversible mild neutropenia; in rare circumstances, thrombocytopenia has been associated with metronidazole treatment. We present a case of aplastic anemia related to the extended use of metronidazole.

Language: eng

Rights:

Pmid: 30727812

Tags: Humans; Thrombocytopenia; Anti-Bacterial Agents/adverse effects; *Anemia, Aplastic/chemically induced/diagnosis; aplastic anemia; hematologic dyscrasia; metronidazole; Metronidazole/adverse effects; neutropenia

Link: https://pubmed.ncbi.nlm.nih.gov/30727812/

PubMed
May 12, 2025
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Clinical and cost-effectiveness of lithium versus quetiapine augmentation for treatment-resistant depression in adults: LQD a pragmatic randomised controlled trial

Health Technol Assess. 2025 May;29(12):1-118. doi: 10.3310/YQVF5347. ABSTRACT BACKGROUND: Lithium and several atypical antipsychotics are the recommended first-line augmentation options for treatment-resistant depression; however, few studies have compared them directly,…