Unilateral generalized morphea: First case report in Taiwan.
Autor: Lu, Meng-Che; Shyur, Shyh-Dar; Lee, Lee-Wen; Hsu, Timothy
Publication year: 2020
Asian Pacific journal of allergy and immunology
issn:0125-877X
doi: 10.12932/AP-020818-0387
Abstract:
Generalised morphea (GM) is a subtype of localised scleroderma that usually manifests with bilateral involvement. Unilateral generalised morphea (UGM) is a rare variant of GM. This is a case report of a Taiwanese girl with UGM over the left side of her body. She presented with hyperpigmentation, tightness, and skin atrophy over the left extremities and trunk. Mild range of motion (ROM) limitation over the left knee was also noted. At the clinic, the patient was given oral prednisolone, oral methotrexate (MTX), and oral D-penicillamine. topical emollient and topical glucocorticoids were also given. The dose of oral prednisolone was tapered gradually. All symptoms were improved under the treatment and regular rehabilitation program. To date, there is very little evidence to form the basis for treatment recommendations. This case report provides a treatment option for UGM in the paediatric group without the use of intravenous methylprednisolone pulse therapy.
Language: eng
Rights:
Pmid: 30525738
Tags: Humans; Female; Child; Treatment Outcome; Administration, Oral; Administration, Topical; Skin/*pathology; Taiwan; Emollients/therapeutic use; Methotrexate/*therapeutic use; Hyperpigmentation; Penicillamine/*therapeutic use; Prednisolone/*therapeutic use; Scleroderma, Localized/*diagnosis/drug therapy
Link: https://pubmed.ncbi.nlm.nih.gov/30525738/
