Study Compares Parenteral and Enteral Nutrition in Brain-Injured Patients

  • PubMed
  • May 26, 2025
  • 0 Comments

A recent clinical study evaluated the impact of nutritional support methods on patients with moderate to severe brain injuries. The research involved 51 individuals who had sustained brain injuries and presented with a peak 24-hour Glasgow Coma Scale (GCS) score between 4 and 10 upon hospital admission. These scores typically indicate a serious degree of impairment in consciousness.

Participants were prospectively and randomly assigned to receive one of two forms of nutritional support: total parenteral nutrition (TPN), which involves intravenous delivery of nutrients, or enteral nutrition (EN), which uses a feeding tube to the gastrointestinal tract. The objective of the study was to determine whether the method of nutritional delivery influenced patient recovery outcomes.

The patients were monitored for 18 days following their injury. Throughout this period, researchers evaluated a range of clinical parameters, including metabolic health, risk of infection, gastrointestinal tolerance, and overall recovery. The primary endpoint of the study was functional outcome, assessed using established scales such as the Glasgow Outcome Scale (GOS), which gauges the degree of disability or dependence in daily activities following brain injury.

While complete results of the study were not disclosed in the abstract summary, the rigor of its randomized, prospective design lends weight to its findings. The research contributes valuable insights to critical care practices by highlighting how the mode of nutritional support can influence the recovery trajectories of patients with significant brain trauma.

This study underscores the importance of early nutritional intervention in neurocritical care and may inform future guidelines aimed at optimizing the recovery and survival of patients with traumatic brain injuries.

Source: https:// – Courtesy of the original publisher.

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