Scleroderma “en coup de sabre” With Epilepsy and Uveitis Successfully Treated With Tocilizumab.
Autor: Osminina, Maria; Geppe, Nathalia; Afonina, Elena
Publication year: 2020
Reumatologia clinica
issn:2173-5743
doi: 10.1016/j.reuma.2018.05.001
Abstract:
Case history of a small girl outlet with epilepsy, followed by scleroderma skin damage and uveitis, neurovasculitis with white matter foci in brain on the side of skin lesion in two months, immunologic disease activity. Resistance to conventional immunosuppressive therapy forced us to initiate the treatment with tocilizumab. It was well tolerated and led to significant improvement of brain, ocular and skin manifestations.
Language: spa
Rights: Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.
Pmid: 29929808
Tags: Humans; Female; Child, Preschool; Immunosuppressive Agents/*therapeutic use; Antibodies, Monoclonal, Humanized/*therapeutic use; Epilepsia y uveítis; Epilepsy and uveitis; Epilepsy/drug therapy/*etiology; Esclerodermia «en coup de sabre» con neurovasculitis; Scleroderma “en coup de sabre” with neurovasculitis; Scleroderma, Localized/complications/diagnosis/*drug therapy; Tocilizumab treatment; Tratamiento con tocilizumab; Uveitis/drug therapy/*etiology
Link: https://pubmed.ncbi.nlm.nih.gov/29929808/