Infectious Complications in Patients Who Received High-Volume Plasma Exchange Prior to Liver Transplant: A Case Report.
Autor: Park, Ga Eun; Peck, Kyong Ran; Kim, Jong Man; Kwon, Choon Hyuck David; Joh, Jae-Won; Cho, Duck; Sinn, Dong Hyun
Publication year: 2020
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
issn:2146-8427 1304-0855
doi: 10.6002/ect.2018.0071
Abstract:
Acute liver failure is a rare but life-threatening medical emergency. Despite advancements in medical management, mortality rates of acute liver failure remain high. Currently, liver transplant is the only definitive therapeutic option available. High-volume plasma exchange has been shown to increase transplant-free survival in patients with acute liver failure before liver transplant. However, the occurrence of infectious complications in patients who receive this treatment has not been well studied. We report 2 cases of severe opportunistic infections occurring within 30 days of transplant in patients who underwent high-volume plasma exchange before liver transplant.
Language: eng
Rights:
Pmid: 30696393
Tags: Humans; Aged; Female; Male; Time Factors; Young Adult; Treatment Outcome; Risk Factors; Antiviral Agents/therapeutic use; Immunosuppressive Agents/adverse effects; Liver Transplantation/*adverse effects; Immunocompromised Host; Antifungal Agents/therapeutic use; Cytomegalovirus Infections/diagnosis/drug therapy/immunology/*virology; Invasive Pulmonary Aspergillosis/diagnosis/drug therapy/immunology/*microbiology; Liver Failure, Acute/diagnosis/*therapy; Opportunistic Infections/diagnosis/drug therapy/immunology/*virology; Plasma Exchange/*adverse effects
Link: https://pubmed.ncbi.nlm.nih.gov/30696393/
