Acanthophoraine A, a new pyrrolidine alkaloid from the red alga Acanthophora spicifera.
Autor: Lin, Jia-Li; Liang, Yong-Qian; Liao, Xiao-Jian; Yang, Jian-Ting; Li, Dai-Chun; Huang, Yu-Ling; Jiang, Zhi-Hui; Xu, Shi-Hai; Zhao, Bing-Xin
Publication year: 2020
Natural product research
issn:1478-6427 1478-6419
doi: 10.1080/14786419.2019.1569008
Abstract:
A new pyrrolidine alkaloid, acanthophoraine A (1), along with six known alkaloids (2-7), had been isolated from the red alga Acanthophora spicifera. The structures of these compounds were identified by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 represents the first example of N-isobutyl pyrrolidone with an urea arm. The antimicrobial activity of 1 was also evaluated.[Figure: see text].
Language: eng
Rights:
Pmid: 30784312
Tags: Molecular Structure; Spectrum Analysis; Molecular Conformation; alkaloids; Alkaloids/chemistry/*isolation & purification; Acanthophora spicifera; Anti-Infective Agents/chemistry/isolation & purification/pharmacology; Pyrrolidines/chemistry/*isolation & purification; Red alga; Rhodophyta/*chemistry
Link: https://pubmed.ncbi.nlm.nih.gov/30784312/